Repression of human activation induced cytidine deaminase by miR-93 and miR-155

BACKGROUND: Activation Induced cytidine Deaminase (AID) targets the immunoglobulin genes of activated B cells, where it converts cytidine to uracil to induce mutagenesis and recombination. While essential for immunoglobulin gene diversification, AID misregulation can result in genomic instability an...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Borchert, Glen M, Holton, Nathaniel W, Larson, Erik D
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2011
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163633/
https://ncbi.nlm.nih.gov/pubmed/21831295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-347
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