miR-181b negatively regulates activation-induced cytidine deaminase in B cells

Activated B cells reshape their primary antibody repertoire after antigen encounter by two molecular mechanisms: somatic hypermutation (SHM) and class switch recombination (CSR). SHM and CSR are initiated by activation-induced cytidine deaminase (AID) through the deamination of cytosine residues on...

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Detalhes bibliográficos
Main Authors: de Yébenes, Virginia G., Belver, Laura, Pisano, David G., González, Susana, Villasante, Aranzazu, Croce, Carlo, He, Lin, Ramiro, Almudena R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Brief Definitive Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556787/
https://ncbi.nlm.nih.gov/pubmed/18762567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20080579
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