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Integrin subunits alpha5 and alpha6 regulate cell cycle by modulating the chk1 and Rb/E2F pathways to affect breast cancer metastasis

BACKGROUND: Although integrins have been implicated in the progression of breast cancer, the exact mechanism whereby they exert this regulation is clearly not understood. To understand the role of integrins in breast cancer, we examined the expression levels of several integrins in mouse breast canc...

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Bibliografski detalji
Glavni autori: Wang, Yanfang, Shenouda, Sylvia, Baranwal, Somesh, Rathinam, Rajamani, Jain, Prachi, Bao, Lili, Hazari, Siddhartha, Dash, Srikanta, Alahari, Suresh K
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163626/
https://ncbi.nlm.nih.gov/pubmed/21752283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-84
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