A Systems Biology Strategy for Predicting Similarities and Differences of Drug Effects: Evidence for Drug-specific Modulation of Inflammation in Atherosclerosis

BACKGROUND: Successful drug development has been hampered by a limited understanding of how to translate laboratory-based biological discoveries into safe and effective medicines. We have developed a generic method for predicting the effects of drugs on biological processes. Information derived from...

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Main Authors: Kleemann, Robert, Bureeva, Svetlana, Perlina, Ally, Kaput, Jim, Verschuren, Lars, Wielinga, Peter Y, Hurt-Camejo, Eva, Nikolsky, Yuri, van Ommen, Ben, Kooistra, Teake
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163556/
https://ncbi.nlm.nih.gov/pubmed/21838869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-5-125
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