High-resolution imaging of the immunological synapse and T-cell receptor microclustering through microfabricated substrates

T-cell activation via antigen presentation is associated with the formation of a macromolecular membrane assembly termed the immunological synapse (IS). The genesis of the IS and the onset of juxtacrine signalling is characterized by the formation of cell membrane microclusters and the organization...

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Bibliographische Detailangaben
Hauptverfasser: Biggs, M. J. P., Milone, M. C., Santos, L. C., Gondarenko, A., Wind, S. J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Royal Society 2011
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163423/
https://ncbi.nlm.nih.gov/pubmed/21490003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2011.0025
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