載入...
Design, Synthesis and Biological Evaluation of Novel Pyrimido[4,5-d]pyrimidine CDK2 Inhibitors as Anti-Tumor Agents
A series of 2,5,7-trisubstituted pyrimido[4,5-d]pyrimidine cyclin-dependent kinase (CDK2) inhibitors is designed and synthesized. 6-Amino-2-thiouracil is reacted with an aldehyde and thiourea to prepare the pyrimido[4,5-d]-pyrimidines. Alkylation and amination of the latter ones give different amino...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Österreichische Apotheker-Verlagsgesellschaft
2011
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3163380/ https://ncbi.nlm.nih.gov/pubmed/21886895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.1103-16 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|