Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression

The transcriptional corepressor SMRT functions by mediating the repressive effect of transcription factors involved in diverse signaling pathways. The mechanism by which SMRT represses basal transcription has been proposed to involve the indirect recruitment of histone deacetylase HDAC1 via the adap...

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Bibliographic Details
Main Authors: Kao, Hung-Ying, Downes, Michael, Ordentlich, Peter, Evans, Ronald M.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2000
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC316336/
https://ncbi.nlm.nih.gov/pubmed/10640276
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