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Proofreading deficiency of Pol I increases the levels of spontaneous rpoB mutations in E. coli
The fidelity role of DNA polymerase I in chromosomal DNA replication in E. coli was investigated using the rpoB forward target. These experiments indicated that in a strain carrying a proofreading-exonuclease-defective form of Pol I (polAexo mutant) the frequency of rpoB mutations increased by about...
Gorde:
| Egile Nagusiak: | , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2011
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3163159/ https://ncbi.nlm.nih.gov/pubmed/21459099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2011.03.011 |
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