Fluorescent DNA Nanotags Featuring Covalently Attached Intercalating Dyes: Synthesis, Antibody Conjugation and Intracellular Imaging

We have synthesized fluorescent DNA duplexes featuring multiple thiazole orange (TO) intercalating dyes covalently attached to the DNA via a triazole linkage. The intercalating dyes stabilize the duplex against thermal denaturation and show bright fluorescence in the green. The emission color can be...

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Detalhes bibliográficos
Main Authors: Stadler, Andrea L., Santos, Junriz Delos, Stensrud, Elizabeth S., Dembska, Anna, Silva, Gloria L., Liu, Shengpeng, Shank, Nathaniel I., Kunttas-Tatli, Ezgi, Sobers, Courtney J., Gramlich, Philipp M. E., Carell, Thomas, Peteanu, Linda A., McCartney, Brooke M., Armitage, Bruce A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163149/
https://ncbi.nlm.nih.gov/pubmed/21755981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc100485f
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