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Enantioselective Synthesis of (−)-Jiadifenin, a Potent Neurotrophic Modulator

[Image: see text] The first enantioselective synthesis of (−)-jiadifenin (1), a potent neurite outgrowth promoter isolated from Illicium species, is described. The synthetic strategy builds upon bicyclic motif 6 that represents the AB ring of the natural product and proceeds in 19 steps and 1.1% ove...

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Detalhes bibliográficos
Main Authors: Trzoss, Lynnie, Xu, Jing, Lacoske, Michelle H., Mobley, William C., Theodorakis, Emmanuel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163030/
https://ncbi.nlm.nih.gov/pubmed/21812392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol201742j
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