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Enantioselective Total Synthesis of (−)-Jiadifenolide
The first total synthesis of jiadifenolide (1), a potent neurotrophic modulator, has been reported. Highlights of the synthesis include: construction of the B ring via an asymmetric Robinson annulation; assembly of the E ring lactone via a novel acid-induced cascade reaction; and Pd(0)-mediated carb...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3159889/ https://ncbi.nlm.nih.gov/pubmed/21400650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201100313 |
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