ss-TEA: Entropy based identification of receptor specific ligand binding residues from a multiple sequence alignment of class A GPCRs

BACKGROUND: G-protein coupled receptors (GPCRs) are involved in many different physiological processes and their function can be modulated by small molecules which bind in the transmembrane (TM) domain. Because of their structural and sequence conservation, the TM domains are often used in bioinform...

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Detalhes bibliográficos
Main Authors: Sanders, Marijn PA, Fleuren, Wilco WM, Verhoeven, Stefan, van den Beld, Sven, Alkema, Wynand, de Vlieg, Jacob, Klomp, Jan PG
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162937/
https://ncbi.nlm.nih.gov/pubmed/21831265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-332
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