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Mechanism-related circulating proteins as biomarkers for clinical outcome in patients with unresectable hepatocellular carcinoma receiving sunitinib

BACKGROUND: Several proteins that promote angiogenesis are overexpressed in hepatocellular carcinoma (HCC) and have been implicated in disease pathogenesis. Sunitinib has antiangiogenic activity and is an oral multitargeted inhibitor of vascular endothelial growth factor receptors (VEGFRs)-1, -2, an...

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Detalhes bibliográficos
Main Authors: Harmon, Charles S, DePrimo, Samuel E, Raymond, Eric, Cheng, Ann-Lii, Boucher, Eveline, Douillard, Jean-Yves, Lim, Ho Y, Kim, Jun S, Lechuga, Maria José, Lanzalone, Silvana, Lin, Xun, Faivre, Sandrine
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162912/
https://ncbi.nlm.nih.gov/pubmed/21787417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-120
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