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Sunitinib in advanced pancreatic neuroendocrine tumors: latest evidence and clinical potential

Based on preclinical data available in the RIP1-Tag2 transgenic mouse model, sunitinib is an inhibitor of angiogenesis in pancreatic neuroendocrine tumors blocking vascular endothelial growth factor receptors and platelet-derived growth factor receptors in endothelial cells and pericytes, respective...

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Detalhes bibliográficos
Main Authors: Delbaldo, Catherine, Faivre, Sandrine, Dreyer, Chantal, Raymond, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244202/
https://ncbi.nlm.nih.gov/pubmed/22229044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758834011428147
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