NMD and microRNA expression profiling of the HPCX1 locus reveal MAGEC1 as a candidate prostate cancer predisposition gene

BACKGROUND: Several predisposition loci for hereditary prostate cancer (HPC) have been suggested, including HPCX1 at Xq27-q28, but due to the complex structure of the region, the susceptibility gene has not yet been identified. METHODS: In this study, nonsense-mediated mRNA decay (NMD) inhibition wa...

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Main Authors: Mattila, Henna, Schindler, Martin, Isotalo, Jarkko, Ikonen, Tarja, Vihinen, Mauno, Oja, Hannu, Tammela, Teuvo LJ, Wahlfors, Tiina, Schleutker, Johanna
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162583/
https://ncbi.nlm.nih.gov/pubmed/21810217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-327
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