Amyloid-beta transporter expression at the blood-CSF barrier is age-dependent

BACKGROUND: Age is the major risk factor for many neurodegenerative diseases, including Alzheimer's disease (AD). There is an accumulation of amyloid-beta peptides (Aβ) in both the AD brain and the normal aging brain. Clearance of Aβ from the brain occurs via active transport at the blood-brain...

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Autori principali: Pascale, Crissey L, Miller, Miles C, Chiu, Catherine, Boylan, Matthew, Caralopoulos, Ilias N, Gonzalez, Liliana, Johanson, Conrad E, Silverberg, Gerald D
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162580/
https://ncbi.nlm.nih.gov/pubmed/21740544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-8118-8-21
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