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Inferring causal genomic alterations in breast cancer using gene expression data

BACKGROUND: One of the primary objectives in cancer research is to identify causal genomic alterations, such as somatic copy number variation (CNV) and somatic mutations, during tumor development. Many valuable studies lack genomic data to detect CNV; therefore, methods that are able to infer CNVs f...

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Detalhes bibliográficos
Main Authors: Tran, Linh M, Zhang, Bin, Zhang, Zhan, Zhang, Chunsheng, Xie, Tao, Lamb, John R, Dai, Hongyue, Schadt, Eric E, Zhu, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162519/
https://ncbi.nlm.nih.gov/pubmed/21806811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-5-121
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