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Liver mitochondrial dysfunction is reverted by insulin-like growth factor II (IGF-II) in aging rats

BACKGROUND: Serum IGF-I and IGF-II levels decline with age. IGF-I replacement therapy reduces the impact of age in rats. We have recently reported that IGF-II is able to act, in part, as an analogous of IGF-I in aging rats reducing oxidative damage in brain and liver associated with a normalization...

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Detalhes bibliográficos
Main Authors: Garcia-Fernandez, Maria, Sierra, Inma, Puche, Juan E, Guerra, Lucia, Castilla-Cortazar, Inma
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162510/
https://ncbi.nlm.nih.gov/pubmed/21798010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-123
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