Hepatoprotection and neuroprotection induced by low doses of IGF-II in aging rats

BACKGROUND: GH and IGFs serum levels decline with age. Age-related changes appear to be associated to decreases in these anabolic hormones. We have previously demonstrated that IGF-I replacement therapy improves insulin resistance, lipid metabolism and reduces oxidative damage (in brain and liver) i...

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Main Authors: Castilla-Cortázar, Inma, García-Fernández, María, Delgado, Gloria, Puche, Juan E, Sierra, Inma, Barhoum, Rima, González-Barón, Salvador
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150260/
https://ncbi.nlm.nih.gov/pubmed/21733157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-103
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