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Fatty Acid Synthase Modulates Homeostatic Responses to Myocardial Stress

Fatty acid synthase (FAS) promotes energy storage through de novo lipogenesis and participates in signaling by the nuclear receptor PPARα in noncardiac tissues. To determine if de novo lipogenesis is relevant to cardiac physiology, we generated and characterized FAS knockout in the myocardium (FASKa...

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書誌詳細
主要な著者: Razani, Babak, Zhang, Haixia, Schulze, P. Christian, Schilling, Joel D., Verbsky, John, Lodhi, Irfan J., Topkara, Veli K., Feng, Chu, Coleman, Trey, Kovacs, Attila, Kelly, Daniel P., Saffitz, Jeffrey E., Dorn, Gerald W., Nichols, Colin G., Semenkovich, Clay F.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162454/
https://ncbi.nlm.nih.gov/pubmed/21757749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.230508
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