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Crystal Structure of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associated Csn2 Protein Revealed Ca(2+)-dependent Double-stranded DNA Binding Activity

Clustered regularly interspaced short palindromic repeats (CRISPR) and their associated protein genes (cas genes) are widespread in bacteria and archaea. They form a line of RNA-based immunity to eradicate invading bacteriophages and malicious plasmids. A key molecular event during this process is t...

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Detalhes bibliográficos
Main Authors: Nam, Ki Hyun, Kurinov, Igor, Ke, Ailong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162437/
https://ncbi.nlm.nih.gov/pubmed/21697083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.256263
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