Crystal Structure of Human ISG15 Protein in Complex with Influenza B Virus NS1B

ISG15 (interferon-stimulated gene 15), the first ubiquitin-like protein (UBL) identified, has emerged as an important cellular antiviral factor. It consists of two UBL domains with a short linker between them. The covalent attachment of ISG15 to host and viral proteins to modify their functions, sim...

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Bibliographic Details
Main Authors: Li, Liang, Wang, Dongli, Jiang, Yinan, Sun, Jianfeng, Zhang, Senyan, Chen, Yuanyuan, Wang, Xinquan
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162384/
https://ncbi.nlm.nih.gov/pubmed/21757684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C111.257899
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