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Nicotinamide Mononucleotide Adenylyl Transferase-Mediated Axonal Protection Requires Enzymatic Activity But Not Increased Levels of Neuronal Nicotinamide Adenine Dinucleotide

Axonal degeneration is a hallmark of many neurological disorders. Studies in animal models of neurodegenerative diseases indicate that axonal degeneration is an early event in the disease process, and delaying this process can lead to decreased progression of the disease and survival extension. Over...

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Autors principals: Sasaki, Yo, Vohra, Bhupinder P. S., Lund, Frances E., Milbrandt, Jeffrey
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162248/
https://ncbi.nlm.nih.gov/pubmed/19403820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5469-08.2009
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