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The Evolution of MDM2 family genes
MDM2 and MDM4 are proto-oncoproteins that bind to and inhibit members of the p53 protein family, p53, p73 and possibly p63. p53 is a mammalian tumor suppressor and p63 and p73 are critical for development. With the sequencing of genomes from multiple organisms there is mounting evidence for a consen...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3162079/ https://ncbi.nlm.nih.gov/pubmed/21762762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2011.06.030 |
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