ACE as a Mechanosensor to Shear Stress Influences the Control of Its Own Regulation via Phosphorylation of Cytoplasmic Ser(1270)

OBJECTIVES: We tested whether angiotensin converting enzyme (ACE) and phosphorylation of Ser(1270) are involved in shear-stress (SS)-induced downregulation of the enzyme. METHODS AND RESULTS: Western blotting analysis showed that SS (18 h, 15 dyn/cm(2)) decreases ACE expression and phosphorylation a...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Barauna, Valerio Garrone, Campos, Luciene Cristina Gastalho, Miyakawa, Ayumi Aurea, Krieger, Jose Eduardo
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161988/
https://ncbi.nlm.nih.gov/pubmed/21901117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022803
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky