Nuclear Factor-κB–Dependent Epithelial to Mesenchymal Transition Induced by HIF-1α Activation in Pancreatic Cancer Cells under Hypoxic Conditions

BACKGROUND: Epithelial to mesenchymal transition (EMT) induced by hypoxia is one of the critical causes of treatment failure in different types of human cancers. NF-κB is closely involved in the progression of EMT. Compared with HIF-1α, the correlation between NF-κB and EMT during hypoxia has been l...

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Autors principals: Cheng, Zhuo-Xin, Sun, Bei, Wang, Shuang-Jia, Gao, Yue, Zhang, Ying-Mei, Zhou, Hao-Xin, Jia, Guang, Wang, Yong-Wei, Kong, Rui, Pan, Shang-Ha, Xue, Dong-Bo, Jiang, Hong-Chi, Bai, Xue-Wei
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161785/
https://ncbi.nlm.nih.gov/pubmed/21887310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023752
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