A novel genetically-obese rat model with elevated 11beta-hydroxysteroid dehydrogenase type 1 activity in subcutaneous adipose tissue

11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) catalyzes the conversion of inactive glucocorticoids to active glucocorticoids and plays an important role in the development of obesity and metabolic syndrome. 11β-HSD1 activity is lower in liver and higher in omental adipose tissue of obese rodent...

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Main Authors: Prasad, Sakamuri SS Vara, Prashanth, Anamthathmakula, Kumar, Chodavarapu Pavan, Reddy, Sirisha J, Giridharan, Nappan V, Vajreswari, Ayyalasomayajula
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Short Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161380/
https://ncbi.nlm.nih.gov/pubmed/21083914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-9-132
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