Dietary fatty acid composition alters 11β-hydroxysteroid dehydrogenase type 1 gene expression in rat retroperitoneal white adipose tissue

The enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) amplifies intracellular glucocorticoid action by converting inactive glucocorticoids to their active forms in vivo. Adipose-specific overexpression of 11β-HSD1 induces metabolic syndrome in mice, whereas 11β-HSD1 null mice are resistant t...

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Detalhes bibliográficos
Main Authors: Vara Prasad, Sakamuri SS, Jeya Kumar, Shanmugam S, Kumar, Putcha Uday, Qadri, Syed SYH, Vajreswari, Ayyalasomayajula
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Short Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2959202/
https://ncbi.nlm.nih.gov/pubmed/20932307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-9-111
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