Hepatocellular Carcinoma Immunopathogenesis: Clinical Evidence for Global T Cell Defects and an Immunomodulatory Role for Soluble CD25 (sCD25)

BACKGROUND: The mechanisms involved in hepatocellular carcinoma (HCC) establishing an immunologically tolerogenic tumor environment remain poorly characterized. AIM: This study evaluates effector T cell responses and soluble IL-2 receptor alpha chains (sCD25) in relation to HCC stage/survival and ch...

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Autors principals: Cabrera, Roniel, Ararat, Miguel, Cao, Mengde, Xu, Yiling, Wasserfall, Clive, Atkinson, Mark A., Liu, Chen, Nelson, David R.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161029/
https://ncbi.nlm.nih.gov/pubmed/19714465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-009-0955-5
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