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Immune modulation of effector CD4+ and regulatory T cell function by sorafenib in patients with hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a difficult to treat cancer characterized by poor tumor immunity with only one approved systemic drug, sorafenib. If novel combination treatments are to be developed with immunological agents, the effects of sorafenib on tumor immunity are important to understand. I...

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Detalhes bibliográficos
Main Authors: Cabrera, Roniel, Ararat, Miguel, Xu, Yiling, Brusko, Todd, Wasserfall, Clive, Atkinson, Mark A., Chang, Lung Ji, Liu, Chen, Nelson, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3863727/
https://ncbi.nlm.nih.gov/pubmed/23223899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-012-1380-8
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