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Immune modulation of effector CD4+ and regulatory T cell function by sorafenib in patients with hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a difficult to treat cancer characterized by poor tumor immunity with only one approved systemic drug, sorafenib. If novel combination treatments are to be developed with immunological agents, the effects of sorafenib on tumor immunity are important to understand. I...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Cabrera, Roniel, Ararat, Miguel, Xu, Yiling, Brusko, Todd, Wasserfall, Clive, Atkinson, Mark A., Chang, Lung Ji, Liu, Chen, Nelson, David R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer-Verlag 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3863727/
https://ncbi.nlm.nih.gov/pubmed/23223899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-012-1380-8
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