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Stops making sense: translational trade-offs and stop codon reassignment
BACKGROUND: Efficient gene expression involves a trade-off between (i) premature termination of protein synthesis; and (ii) readthrough, where the ribosome fails to dissociate at the terminal stop. Sense codons that are similar in sequence to stop codons are more susceptible to nonsense mutation, an...
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| Päätekijät: | , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
BioMed Central
2011
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3161013/ https://ncbi.nlm.nih.gov/pubmed/21801361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-11-227 |
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