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Enhanced interrogation: emerging strategies for cell signaling inhibition
Here we summarize recent and developing chemical approaches for modulating signaling pathways. In particular, we discuss targeting mutant signaling proteins, disrupting protein-protein interactions in cellular signaling networks, designing bivalent inhibitors of signaling proteins and identifying al...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3160762/ https://ncbi.nlm.nih.gov/pubmed/20520657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb0610-646 |
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