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Altered Ryanodine Receptor Expression in Mild Cognitive Impairment and Alzheimer’s Disease

Intracellular Ca(2+) dysregulation is an underlying component of Alzheimer’s disease (AD) pathophysiology, and recent evidence implicates the ryanodine receptor (RyR) in the disease pathway. Three genes code for different RyR isoforms and each gene transcript gives rise to several alternatively spli...

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Detalhes bibliográficos
Main Authors: Bruno, Angela, Huang, Jeff, Bennett, David A., Marr, Robert, Hastings, Michelle L., Stutzmann, Grace E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160507/
https://ncbi.nlm.nih.gov/pubmed/21531043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2011.03.011
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