Postnatal loss of Dlk1 imprinting in stem cells and niche-astrocytes regulates neurogenesis

The gene for the atypical Notch ligand Delta-like homologue 1 (Dlk1) encodes membrane-bound and secreted isoforms functioning in multiple developmental processes in vitro and in vivo. Dlk1, a member of a cluster of imprinted genes, is expressed from the paternally-inherited chromosome(1,2). Here we...

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Main Authors: Ferrón, Sacri R., Charalambous, Marika, Radford, Elizabeth, McEwen, Kirsten, Wildner, Hendrik, Hind, Eleanor, Morante-Redolat, Jose Manuel, Laborda, Jorge, Guillemot, Francois, Bauer, Steven R., Fariñas, Isabel, Ferguson-Smith, Anne C
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160481/
https://ncbi.nlm.nih.gov/pubmed/21776083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10229
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