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P38 Mitogen-Activated Protein Kinase Inhibitor, FR167653, Inhibits Parathyroid Hormone Related Protein-Induced Osteoclastogenesis and Bone Resorption

p38 mitogen-activated protein kinase (MAPK) acts downstream in the signaling pathway that includes receptor activator of NF-κB (RANK), a powerful inducer of osteoclast formation and activation. We investigated the role of p38 MAPK in parathyroid hormone related protein (PTHrP)-induced osteoclastogen...

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Detalhes bibliográficos
Main Authors: Tao, Huiren, Okamoto, Mina, Nishikawa, Masataka, Yoshikawa, Hideki, Myoui, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160289/
https://ncbi.nlm.nih.gov/pubmed/21886782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023199
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