FR167653, a p38 mitogen-activated protein kinase inhibitor, aggravates experimental colitis in mice

AIM: To investigate the effects of FR167653 on the development of dextran sulfate sodium (DSS)-induced colitis in mice. METHODS: BALB/c mice were fed rodent chow containing 3.5% (wt/wt) DSS. The recipient mice underwent intra-peritoneal injection of vehicles or FR167653 (30 mg/kg per day). The mice...

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Bibliographische Detailangaben
Hauptverfasser: Nishimura, Takashi, Andoh, Akira, Nishida, Atsushi, Shioya, Makoto, Koizumi, Yuhsuke, Tsujikawa, Tomoyuki, Fujiyama, Yoshihide
Format: Artigo
Sprache:Inglês
Veröffentlicht: The WJG Press and Baishideng 2008
Schlagworte:
Basic Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751895/
https://ncbi.nlm.nih.gov/pubmed/18855984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.14.5851
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