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Identification and Quantification of DNA Adducts in the Oral Tissues of Mice Treated with the Environmental Carcinogen Dibenzo[a,l]pyrene by HPLC-MS/MS

Tobacco smoking is one of the leading causes for oral cancer. Dibenzo[a,l]pyrene (DB[a,l]P), an environmental pollutant and a tobacco smoke constituent, is the most carcinogenic polycyclic aromatic hydrocarbon (PAH) tested to date in several animal models (target organs: skin, lung, ovary and mammar...

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Bibliografische gegevens
Hoofdauteurs: Zhang, Shang-Min, Chen, Kun-Ming, Aliaga, Cesar, Sun, Yuan-Wan, Lin, Jyh-Ming, Sharma, Arun K., Amin, Shantu, El-Bayoumy, Karam
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160270/
https://ncbi.nlm.nih.gov/pubmed/21736370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx200188j
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