Effects of Black Raspberry on Dibenzo[a,l]Pyrene Diol Epoxide Induced DNA Adducts, Mutagenesis and Tumorigenesis in the Mouse Oral Cavity

We previously showed that metabolic activation of the environmental and tobacco smoke constituent dibenzo[a,l]pyrene (DB[a,l]P) to its active fjord region diol epoxide (DB[a,l]PDE) is required to induce DNA damage, mutagenesis and squamous cell carcinoma (SCC) in the mouse oral cavity. In contrast t...

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Publicado en:Cancer Prev Res (Phila)
Autores principales: Chen, Kun-Ming, Guttenplan, Joseph B., Sun, Yuan-Wan, Cooper, Timothy, Shalaby, Nora AE, Kosinska, Wieslawa, Benitez, Gabrielle, Aliaga, Cesar, Zhu, Junjia, Liao, Jason, Gowda, Krishne, Amin, Shantu, Stoner, Gary, El-Bayoumy, Karam
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839973/
https://ncbi.nlm.nih.gov/pubmed/29158340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-17-0278
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