A yeast BH3-only protein mediates the mitochondrial pathway of apoptosis

Mitochondrial outer membrane permeabilization is a watershed event in the process of apoptosis, which is tightly regulated by a series of pro- and anti-apoptotic proteins belonging to the BCL-2 family, each characteristically possessing a BCL-2 homology domain 3 (BH3). Here, we identify a yeast prot...

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Autors principals: Büttner, Sabrina, Ruli, Doris, Vögtle, F-Nora, Galluzzi, Lorenzo, Moitzi, Barbara, Eisenberg, Tobias, Kepp, Oliver, Habernig, Lukas, Carmona-Gutierrez, Didac, Rockenfeller, Patrick, Laun, Peter, Breitenbach, Michael, Khoury, Chamel, Fröhlich, Kai-Uwe, Rechberger, Gerald, Meisinger, Chris, Kroemer, Guido, Madeo, Frank
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160254/
https://ncbi.nlm.nih.gov/pubmed/21673659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.197
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