Cardiac-restricted angiotensin-converting enzyme overexpression causes conduction defects and connexin dysregulation

Renin-angiotensin (RAS) system activation is associated with an increased risk of sudden death. Previously, we used cardiac-restricted angiotensin-converting enzyme (ACE) overexpression to construct a mouse model of RAS activation. These ACE 8/8 mice die prematurely and abruptly. Here, we have inves...

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Detalhes bibliográficos
Main Authors: Kasi, Vijaykumar S., Xiao, Hong D., Shang, Lijuan L., Iravanian, Shahriar, Langberg, Jonathan, Witham, Emily A., Jiao, Zhe, Gallego, Carlos J., Bernstein, Kenneth E., Dudley, Samuel C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160110/
https://ncbi.nlm.nih.gov/pubmed/17337599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00684.2006
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