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Shadows of complexity: what biological networks reveal about epistasis and pleiotropy

Pleiotropy, in which one mutation causes multiple phenotypes, has traditionally been seen as a deviation from the conventional observation in which one gene affects one phenotype. Epistasis, or gene-gene interaction, has also been treated as an exception to the Mendelian one gene-one phenotype parad...

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Detalhes bibliográficos
Main Authors: Tyler, Anna L., Asselbergs, Folkert W., Williams, Scott M., Moore, Jason H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159922/
https://ncbi.nlm.nih.gov/pubmed/19204994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.200800022
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