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Shadows of complexity: what biological networks reveal about epistasis and pleiotropy

Pleiotropy, in which one mutation causes multiple phenotypes, has traditionally been seen as a deviation from the conventional observation in which one gene affects one phenotype. Epistasis, or gene-gene interaction, has also been treated as an exception to the Mendelian one gene-one phenotype parad...

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Bibliografiske detaljer
Main Authors: Tyler, Anna L., Asselbergs, Folkert W., Williams, Scott M., Moore, Jason H.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159922/
https://ncbi.nlm.nih.gov/pubmed/19204994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.200800022
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