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A SOCS-1 Promoter Variant is Associated with Total Serum IgE Levels()

SOCS-1 is a critical regulator of multiple signaling pathways, including those activated by cytokines that regulate immunoglobulin heavy chain class switching to IgE. Analysis of mice with mutations in the SOCS-1 gene demonstrated that IgE levels increase with loss of SOCS-1 alleles. This suggested...

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Detaylı Bibliyografya
Asıl Yazarlar:	Mostecki, Justin, Cassel, Suzanne L., Klimecki, Walter T., Stern, Debra A., Knisz, Judit, Iwashita, Sachiyo, Graves, Penelope, Miller, Rachel L., van Peer, Maartje, Halonen, Marilyn, Martinez, Fernando D., Vercelli, Donata, Rothman, Paul B.
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	2011
Konular:	Article
Online Erişim:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3159751/ https://ncbi.nlm.nih.gov/pubmed/21795592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902569
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A SOCS-1 Promoter Variant is Associated with Total Serum IgE Levels()

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