Zinc finger protein TTP interacts with CCL3 mRNA and regulates tissue inflammation

Zinc finger protein tristetraprolin (TTP) modulates macrophage inflammatory activity by destabilizing cytokine mRNAs. Here, through a screen of TTP-bound mRNAs in activated human macrophages, we have identified CC chemokine ligand 3 (CCL3) mRNA as the most abundantly bound TTP target mRNA and have c...

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Detaylı Bibliyografya
Asıl Yazarlar: Kang, Ju-Gyeong, Amar, Marcelo J., Remaley, Alan T., Kwon, Jaeyul, Blackshear, Perry J., Wang, Ping-yuan, Hwang, Paul M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159726/
https://ncbi.nlm.nih.gov/pubmed/21784977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101149
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