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Peptides from Phage Display Library Modulate Gene Expression in Mesenchymal Cells and Potentiate Osteogenesis in Unicortical Bone Defects

Two novel synthetic peptides accelerate bone formation and can be delivered using a collagen matrix. The aim of this study was to investigate the effects on bone repair in a unicortical defect model. Treatment of mesenchymal cells produced an increase in alkaline phosphatase activity, showed nodule...

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Détails bibliographiques
Auteurs principaux: Balian, Gary, Beck, Gina, Madhu, Vedavathi, Sikes, Robert, Cui, Quanjun, Liang, Haixiang, Bush, Joshua
Format: Artigo
Langue:Inglês
Publié: MyJove Corporation 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159677/
https://ncbi.nlm.nih.gov/pubmed/21178970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/2362
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