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BMP-Non-Responsive Sca1(+)CD73(+)CD44(+) Mouse Bone Marrow Derived Osteoprogenitor Cells Respond to Combination of VEGF and BMP-6 to Display Enhanced Osteoblastic Differentiation and Ectopic Bone Formation

Clinical trials on fracture repair have challenged the effectiveness of bone morphogenetic proteins (BMPs) but suggest that delivery of mesenchymal stem cells (MSCs) might be beneficial. It has also been reported that BMPs could not increase mineralization in several MSCs populations, which adds amb...

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Библиографические подробности
Главные авторы: Madhu, Vedavathi, Li, Ching-Ju, Dighe, Abhijit S., Balian, Gary, Cui, Quanjun
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105618/
https://ncbi.nlm.nih.gov/pubmed/25048464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103060
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