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Up a lymphoid blind alley: Does CALM/AF10 disturb Ikaros during leukemogenesis?

The Ikaros gene is required for normal development of lymphocytes and frequent intragenic deletions of Ikaros have been identified in acute lymphoblastic leukemia. However, little is known about the role of Ikaros in myeloid malignancies. Here we discuss the role of Ikaros as a lineage master regula...

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Hlavní autoři: Greif, Philipp A, Bohlander, Stefan K
Médium: Artigo
Jazyk:Inglês
Vydáno: Baishideng Publishing Group Co., Limited 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159521/
https://ncbi.nlm.nih.gov/pubmed/21765976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4331/wjbc.v2.i6.115
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