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Composition of yeast snRNPs and snoRNPs in the absence of trimethylguanosine caps reveals nuclear cap binding protein as a gained U1 component implicated in the cold-sensitivity of tgs1Δ cells

Small nuclear and nucleolar RNAs that program pre-mRNA splicing and rRNA processing have a signature 5′-trimethylguanosine (TMG) cap. Whereas the mechanism of TMG synthesis by Tgs1 methyltransferase has been elucidated, we know little about whether or how RNP biogenesis, structure and function are p...

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Autores principales: Schwer, Beate, Erdjument-Bromage, Hediye, Shuman, Stewart
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159458/
https://ncbi.nlm.nih.gov/pubmed/21558325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr279
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