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A genetically humanized mouse model for hepatitis C virus infection

Hepatitis C virus (HCV) remains a major medical problem. Antiviral treatment is only partially effective and a vaccine does not exist. Development of more effective therapies has been hampered by the lack of a suitable small animal model. While xenotransplantation of immunodeficient mice with human...

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Detalhes bibliográficos
Main Authors: Dorner, Marcus, Horwitz, Joshua A., Robbins, Justin B., Barry, Walter T., Feng, Qian, Mu, Kathy, Jones, Christopher T., Schoggins, John W., Catanese, Maria Teresa, Burton, Dennis R., Law, Mansun, Rice, Charles M., Ploss, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159410/
https://ncbi.nlm.nih.gov/pubmed/21654804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10168
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