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Preparation and Characterization of Metformin Hydrochloride — Compritol 888 ATO Solid Dispersion

Metformin hydrochloride (MET) sustained-release solid dispersions (SD) were prepared by the solvent evaporation and closed melt method, using compritol 888 ATO as the polymer with five different drug-carrier ratios. Characterization of solid dispersion was carried out by Fourier Transform Infrared (...

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Detalhes bibliográficos
Main Authors: Jagdale, SC, Patil, SA, Kuchekar, BS, Chabukswar, AR
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159272/
https://ncbi.nlm.nih.gov/pubmed/21897658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0975-1483.83758
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